Table 1 Definition of evaluation categories for different simulated analytes using the total error specification.

From: refineR: A Novel Algorithm for Reference Interval Estimation from Real-World Data

  1. The table shows for each simulated biomarker the ranges of the absolute deviation from the ground truth used for defining the color-coded evaluation categories.
  2. TE total error, RI reference interval.
  3. Legend (adapted from Zierk et al.22): Green (Within ± 1TE)—Appropriate for RI estimation. Yellow (Within ± 2TE)—Appropriate for quality control. Red (Outside ± 2TE)—Inappropriate estimations. Use with caution in select settings.
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