Figure 1

Treatment response related to baseline ctDNA mutations. (A) Kaplan–Meier curves of PFS according to baseline KRAS or NRAS hotspot mutations by ctDNA. (B) Kaplan–Meier curves of PFS according to average VAF changes after treatment. (C) Kaplan–Meier curves of PFS according to average VAF changes and RECIST 1.1 response groups at the time of first response evaluation (log-rank p-value for all groups).