Table 3 Multiple backward stepwise regression analysis for ABI and CIMT as dependent variables.

From: Klotho as a biomarker of subclinical atherosclerosis in patients with moderate to severe chronic kidney disease

 

Adjusted R2

β

Standard error

t

P

ABI

0.537

   

 < 0.0001

Current smokers

 

 − 0.206

0.019

 − 2.735

0.0075

Diabetes mellitus

 

 − 0.163

0.017

 − 2.342

0.0212

Serum IL6 (pg/mL)

 

 − 0.288

0.003

 − 3.454

0.00083

Serum Klotho (pg/mL)

 

0.236

0.000052

2.841

0.0055

PBCs KL mRNA (a.u.)

 

0.238

0.013

2.963

0.0037

CIMT

0.370

   

 < 0.0001

Serum IL6 (pg/mL)

 

0.229

0.139

2.391

0.019

Serum Klotho (pg/mL)

 

 − 0.366

0.000238

 − 3.887

 < 0.001

PBCs KL mRNA (a.u.)

 

 − 0.171

0.0595

 − 1.885

0.041

  1. ABI ankle-brachial index, CIMT carotid intima-media thickness, PBCs peripheral blood cells, IL interleukin, KL Klotho gene.
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