Figure 5

Role of a-FABP in the pathophysiology of heart failure. The hypothetical mechanistic links underlying higher a-FABP, micro-vascular dysfunction, and HFpEF are shown. Heightened central aortic stiffness and impaired myocardial function are key mediators in this pathological process. Ao, aorta, LV, left ventricle. Other abbreviations as Table 1.