Table 2 Univariate and multiple logistic regression analyses of factors associated with max-CIMT ≥ 1.2 mm.

From: Liver fibrosis is associated with carotid atherosclerosis in patients with liver biopsy-proven nonalcoholic fatty liver disease

Factor

Category

Univariate

Multivariate

OR

95% CI

p value

OR

95% CI

p value

Age

≥ 65 years

6.44

3.34–12.42

< 0.01

5.46

2.66–11.19

< 0.01

Gender

Male

1.73

0.98–3.06

0.06

2.36

1.18–4.73

< 0.05

eGFR

< 60 mL/min/1.73m2

2.79

1.12–6.95

< 0.05

   

Total cholesterol

< 220 mg/dL

3.29

1.51–7.14

< 0.01

   

HDL cholesterol

< 40 mg/dL

1.88

0.96–3.69

0.07

   

LDL cholesterol

< 140 mg/dL

3.82

1.91–7.63

< 0.01

   

Triglyceride

< 150 mg/dL

1.08

0.60–1.92

0.80

   

HOMA-IR

≥ 2.5

167

0.88–3.18

0.12

   

Type 2 diabetes mellitus

Presence

2.01

1.12–3.62

< 0.05

   

Hypertension

Presence

2.66

1.49–4.75

< 0.01

2.24

1.13–4.44

< 0.05

Smoking

No

1.36

0.74–2.50

0.33

   

Liver fibrosis

Advanced fibrosis

3.90

1.98–7.66

< 0.01

2.24

1.03–4.86

< 0.05

  1. CIMT carotid intima-media thickness, OR odds ratio, CI confidence interval, eGFR estimated glomerular filtration rate, HDL high-density lipoprotein, LDL low-density lipoprotein, HOMA-IR homeostasis model assessment-insulin resistance.
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