Table 2 Significantly differentially abundant proteins in the F₁^50ppm B × C female newborn brains compared to controls, ranked by adj p val in 50 ppm group. Abundance ratios for these proteins in the F₁^1ppm female newborn brains included. ^a = found in myelin proteome, ^b = involved in RA pathways, ^c = histone 1 subunit.

From: Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior

Protein	Abundance Ratio Adj. P-Value: (1 ppm)/(0 ppm)	Abundance Ratio Adj. P-Value: (50 ppm)/(0 ppm)	Abundances (Grouped): 0 ppm	Abundances (Grouped): 1 ppm	Abundances (Grouped): 50 ppm	1 ppm change to 0 ppm (%)	50 ppm change to 0 ppm (%)
Ldha^a,b	0.973898894	0.000004728	90.9	91.8	117.3	0.990099	29.042904
Pfkl	0.119323304	0.000004768	86.1	98.2	115.7	14.053426	34.37863
Slc6a11	0.046109095	0.000011345	88.7	97.7	113.6	10.146561	28.072153
Nefm^a,b	0.000014534	0.000013915	84.7	104.7	110.6	23.612751	30.578512
Gpi1^a	0.99117914	0.00012503	90.7	92.5	116.9	1.9845645	28.886439
Aldoc^a,b	0.014283746	0.0002136	86.9	102.2	110.8	17.606444	27.502877
Hist1h1e^c	0.680950614	0.000458262	108.9	103.4	87.7	−5.050505	−19.4674
Slc1a3^a,b	0.026706171	0.000459068	94.3	95	110.7	0.7423118	17.391304
Srsf4^b	0.254416432	0.000500359	109.8	102	88.2	−7.103825	−19.67213
Tuba4a^a,b	0.812211612	0.001034191	91	100.3	108.7	10.21978	19.450549
Hpca	0.818093421	0.001676617	92	96.1	111.9	4.4565217	21.630435
Tpi1^a,b	0.995738881	0.001737399	94.3	93.7	111.9	−0.636267	18.663839
Ahsg^b	0.259432391	0.001766066	98.4	86.8	114.8	−11.78862	16.666667
Fxyd6	0.084419728	0.0037873	91.9	98	110.1	6.6376496	19.804135
Ckmt1	0.991151472	0.004356406	94.8	94.8	110.3	0	16.350211
Hist1h1b^c	0.995738881	0.004617561	105.6	108.1	86.2	2.3674242	−18.37121
Hprt	0.926735568	0.004685861	95.2	89.9	114.9	−5.567227	20.693277
Aldoa^a,b	0.937783837	0.004964389	92.4	93.8	113.9	1.5151515	23.268398
Hist1h1d^b,c	0.606980956	0.004964389	108.6	102.1	89.2	−5.985267	−17.86372
Ptma^b	0.080791892	0.004964389	112.2	97.6	90.2	−13.01248	−19.60784
Glul^a,b	0.729109325	0.005102008	91.5	98.8	109.8	7.9781421	20
Prkacb^b	0.063552234	0.005317616	99.5	90.1	110.4	−9.447236	10.954774
Sncb^a	0.585421643	0.005422114	93.9	91	115.1	−3.088392	22.57721
Slc12a5	0.970511751	0.006450782	91.6	95.3	113.1	4.0393013	23.471616
Apoe^b	0.680950614	0.008266455	89.6	96.6	113.7	7.8125	26.897321
Alg2	0.31039933	0.008520425	90.4	98	111.6	8.4070796	23.451327
Apoa1	0.991151472	0.009864999	89.7	94.9	115.4	5.7971014	28.651059
Eno1^a,b	0.674411211	0.010566996	93.7	92.4	113.9	−1.387407	21.558164
Abat^b	0.989354576	0.012954966	92.4	94	113.6	1.7316017	22.943723
Crabp1^b	0.04344094	0.013498454	85.5	103.8	110.7	21.403509	29.473684
Camk2d^a,b	0.580890155	0.018126666	90.3	96.7	113	7.0874862	25.138427
Satb2	0.973898894	0.01885168	108.5	110.1	81.4	1.4746544	−24.97696
Ndrg2^b	0.680375748	0.018905298	94.6	95.9	109.5	1.3742072	15.750529
Dnm1^a,b	0.174291855	0.022293486	93.1	98.7	108.2	6.0150376	16.219119
Trf	0.176950766	0.025109111	96.1	91.7	112.2	−4.578564	16.753382
Vsnl1^a,b	0.909390199	0.029396495	97.2	93.2	109.6	−4.115226	12.757202
Gstm1^a,b	0.989354576	0.031417367	93.9	93	113.1	−0.958466	20.447284
Set	0.031217009	0.031978606	106.2	99	94.8	−6.779661	−10.73446
Syn2^a	0.426588152	0.032509188	88.8	100.9	110.3	13.626126	24.211712
Anxa2^a,b	0.797814818	0.03380452	95.3	95.6	109.1	0.3147954	14.480588
Trp53i11	0.737170178	0.034474205	107.9	103	89.2	−4.541242	−17.33086
Hpcal1^a,b	0.818093421	0.038283218	94.2	96.9	108.9	2.866242	15.605096
Stmn2	0.419569789	0.039318421	89.2	102.9	107.9	15.358744	20.964126
Camk2g^a,b	0.836358682	0.043020031	87.7	102.9	109.3	17.331813	24.629418
Dpp6^a,b	0.389249664	0.04777657	88.9	97.4	113.7	9.5613048	27.896513
Glud1^b	0.474755049	0.048280644	92.8	98.4	108.9	6.0344828	17.349138

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