Table 2 Associations between centrality measures and cognitive and affective measures in PD.

From: Structural network topology and microstructural alterations of the anterior insula associate with cognitive and affective impairment in Parkinson’s disease

 

Left dAI eigenvector centrality

Right dAI eigenvector centrality

Left dAI betweenness centrality

Right dAI betweenness centrality

CAMCOG

rs

− 0.081

0.098

− 0.045

0.199

p-value

0.564

0.487

0.749

0.153

N

53

53

53

53

Fluency

rs

− 0.183

0.024

− 0.160

0.172

p-value

0.189

0.866

0.254

0.219

N

53

53

53

53

PRM

rs

− 0.101

− 0.067

− 0.110

0.005

p-value

0.478

0.635

0.436

0.972

N

52

52

52

52

SSP

rs

− 0.057

− 0.022

0.006

− 0.118

p-value

0.688

0.878

0.964

0.405

N

52

52

52

52

SWM

rs

0.077

0.136

0.033

0.218

p-value

0.585

0.336

0.817

0.120

N

52

52

52

52

IED

rs

− 0.059

− 0.156

− 0.076

− 0.055

p-value

0.682

0.274

0.595

0.700

N

51

51

51

51

VPT

rs

0.262

− 0.112

0.223

− 0.078

p-value

0.061

0.431

0.111

0.584

N

52

52

52

52

BDI

rs

0.277*

− 0.057

0.177

− 0.035

p-value

0.047

0.687

0.210

0.805

N

52

52

52

52

BAI

rs

− 0.111

− 0.208

− 0.163

− 0.286

p-value

0.552

0.261

0.380

0.119

N

31

31

31

31

  1. rs = Spearman correlation; vAI = ventral anterior insula; dAI = dorsal anterior insula. CAMCOG = Cambridge Cognitive Examination revised test battery; PRM = pattern recognition memory; SSP = spatial span; SWM = spatial working memory; IED = the intra-extra dimensional set shift test; VPT = Vienna perseveration test; BAI = Beck Anxiety Inventory; BDI = the Beck Depression Inventory. *p < 0.05.
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