Table 1 Patient characteristics of total cohort and the groups with and without cavitary lesions on CT scan.
From: Evidence for a thromboembolic pathogenesis of lung cavitations in severely ill COVID-19 patients
Cohort (N = 39) | Lung cavitations (N = 22) | No cavitations (N = 17) | p-value | ||||
|---|---|---|---|---|---|---|---|
Age (years, (median, [IQR])) | 67 | [58–76] | 69.5 | [60.5–77.3] | 62 | [61.5–67.75] | 0.047 |
Gender, male (n, %) | 34 | (87%) | 19 | (86%) | 15 | (88%) | 0.86 s |
BMI, kg/m2 (median, [IQR]) | 28 | [25–33] | 27.8 | [24.2–33] | 25.2 | [24.32–28.7] | 0.009 |
Days between symptom onset and ICU admission | 11 | [25–33] | 12 | [6–17] | 11 | [6–19] | 0.49 |
Duration ICU stay, days (median, [IQR]) | 28 | [15.5–39.8] | 30.9 | [27.07–34.25] | 25 | [8.5–30.5] | 0.25 |
Intubation (n, %) | 34 | (87.2%) | 18 | (81%) | 16 | (94%) | 0.47 |
ECMO (n, %) | 10 | (25.6%) | 5 | (22%) | 5 | (29.4%) | 0.22 |
CRRT* (n, %) | 19 | (48.7%) | 12 | (54.5%) | 7 | (50%) | 0.19 |
SOFA-Score (median, [IQR]) | 9 | [7–12] | 10 | [6–11] | 9 | [7–11] | 0.49 |
APACHE-Score (median, [IQR]) | 28 | [22–33] | 28 | [24–34] | 26 | [22–34] | 0.65 |
Secondary ICU referral | 23 | (59.0%) | 11 | (48%) | 12 | (52%) | 0.32 |
PEEP (median, [IQR]) | 17 | [15–18] | 17 | [15–18] | 17 | [15–19] | 0.58 |
PIP (median, [IQR]) | 31 | [29–35] | 32 | [27–35] | 31 | [29–34] | 0.90 |
Delta P (median, [IQR]) | 15 | [12–17] | 17 | [15–18] | 15 | [12–16] | 0.86 |
Preexisting conditions | |||||||
Coronary artery disease (n, %) | 9 | (23.1%) | 7 | (31.2%) | 2 | (11.7%) | 0.44 |
Hypertension (n, %) | 27 | (74.0%) | 14 | (63.63%) | 13 | (76.5%) | 0.12 |
Diabetes mellitus/insulin resistance (n, %) | 14 | (35.9%) | 8 | (36.4%) | 6 | (35.3%) | 0.62 |
Chronic kidney disease (n, %) | 7 | (17.9%) | 3 | (13.6%) | 4 | (23.5%) | 0.42 |
Chronic dialysis (n, %) | 1 | (2.5%) | 0 | (0%) | 1 | (5.9%) | 0.30 |
COPD (n, %) | 10 | (25.6%) | 7 | (31.8%) | 3 | (17.6%) | 0.32 |
