Figure 6
From: NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice
NOTUM overexpression decreases adiposity in chow diet-fed mice. Male C57BL/6J mice were infected with AAV-GFP or AAV-Notum (n = 6 per group) and maintained on a low fat chow diet for 4 weeks before tissue collection. Body weight (a), fat mass (b), lean mass (c), and fat pad weights (d) are shown. Gene expression analysis by qPCR of iWAT (e), n = 6, and iBAT (f), n = 4–5, are shown. Symbols are the same as shown in Fig. 1.
