Table 2 Echocardiographic parameters of WT mice treated with either vehicle or RS504393 after 1 week of transverse aortic constriction (TAC).
TAC Veh | TAC RS | |
---|---|---|
n | 11 | 10 |
Heart rate (bpm) | 455 ± 43 | 421 ± 15 |
LVIDs (mm) | 3.6 ± 0.12 | 3.13 ± 0.15** |
LVIDd (mm) | 4.25 ± 0.09 | 4.04 ± 0.12 |
Ejection fraction (%) | 32.64 ± 2.94 | 45.78 ± 3.58** |
FS (%) | 15.52 ± 1.55 | 23.13 ± 1.98** |
LVAW;s (mm) | 1.27 ± 0.07 | 1.21 ± 0.04 |
LVAW;d (mm) | 1.02 ± 0.05 | 0.89 ± 0.03 |
LVPW;s (mm) | 1.04 ± 0.04 | 1.08 ± 0.03 |
LVPW;d (mm) | 0.87 ± 0.04 | 0.81 ± 0.04 |