Table 2 Echocardiographic parameters of WT mice treated with either vehicle or RS504393 after 1 week of transverse aortic constriction (TAC).

From: Cardiac macrophage subsets differentially regulate lymphatic network remodeling during pressure overload

 

TAC Veh

TAC RS

n

11

10

Heart rate (bpm)

455 ± 43

421 ± 15

LVIDs (mm)

3.6 ± 0.12

3.13 ± 0.15**

LVIDd (mm)

4.25 ± 0.09

4.04 ± 0.12

Ejection fraction (%)

32.64 ± 2.94

45.78 ± 3.58**

FS (%)

15.52 ± 1.55

23.13 ± 1.98**

LVAW;s (mm)

1.27 ± 0.07

1.21 ± 0.04

LVAW;d (mm)

1.02 ± 0.05

0.89 ± 0.03

LVPW;s (mm)

1.04 ± 0.04

1.08 ± 0.03

LVPW;d (mm)

0.87 ± 0.04

0.81 ± 0.04

  1. LVAW;d and LVAW;s indicate left ventricle anterior wall thickness at end diastole (d) or end systole (s) respectively; LVPWd and LVPWs end diastolic and end systolic left posterior wall thickness respectively; LVIDd, diastolic left ventricular dimension; LVIDs, systolic left ventricular dimension and FS, fractional shortening (%). Values shown are mean ± SEM. Significance vs TAC vehicle: **P < 0.01 by t test.