Table 1 Demographic and clinical characteristics of patients assorted by diagnostic categories.

From: Diagnostic and prognostic implications of 2018 guideline for the diagnosis of idiopathic pulmonary fibrosis in clinical practice

Characteristics

IPF

(n = 339)

iNSIP

(n = 98)

cHP

(n = 98)

p value1

p value2

Age, years

62.6 ± 0.4

56.4 ± 1.0

58.7 ± 1.1

 < 0.001

0.008

Male sex

259 (76.4)

51 (52.0)

38 (38.8)

 < 0.001

 < 0.001

Ever smoker

233 (68.7)

50 (51.0)

35 (35.7)

0.002

 < 0.001

Smoking pack-year, years

35.1 ± 1.4

28.3 ± 2.8

28.6 ± 3.2

0.025

0.086

6 min walking distance, m

466.2 ± 6.6

469.4 ± 14.6

473.4 ± 14.4

0.853

0.721

DLCO% predicted

59.9 ± 1.3

55.8 ± 2.8

61.0 ± 3.0

0.041

0.374

FEV1% predicted

79.6 ± 1.3

73.9 ± 2.2

81.7 ± 2.3

0.094

0.052

FVC% predicted

72.9 ± 1.3

71.4 ± 2.3

76.5 ± 2.1

0.074

0.230

Bronchoalveolar lavage†

     

Lymphocytes (%)

13.2 ± 12.3

21.2 ± 19.5

26.2 ± 19.7

 < 0.001

 < 0.001

Neutrophils (%)

10.6 ± 17.9

10.2 ± 15.7

5.8 ± 9.1

0.885

0.018

Eosinophils (%)

4.0 ± 5.6

5.2 ± 7.6

3.3 ± 4.6

0.158

0.317

  1. Data are presented as mean ± standard devation or number (%).
  2. UIP, usual interstitial pneumonia; iNSIP, idiopathic nonspecific interstitial pneumonia; cHP, chronic hypersensitivity pneumonitis; DLCO, diffusing capacity of the lung for carbon monoxide; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.
  3. 1UIP vs iNSIP; 2 UIP vs cHP.
  4. †Analysed in 220 patients with UIP, 65 patients with iNSIP and 86 patients with cHP.
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