Figure 6
Effects of AMPK activators and inhibitors on the partial EMT of HG-stimulated RTECs. (a) Morphological changes of RTECs under different environments. (a) Western blot analysis of E-cadherin and α-SMA after different treatments. The boxes indicate images from different gels, but the samples derived from the same experiment and blots were processed in parallel. (c) Statistical analysis of E-cadherin and α-SMA in each group. *P < 0.01 compared with the LG group, #P < 0.01 compared with the HG without metformin group, △P < 0.01 compared with the HG group, $P < 0.01 compared with HG + Met group, &P < 0.01 compared with HG + AICAR group. Full-length blots were presented in Supplementary Figures.
