Table 1 Adalimumab derived synthetic CDR region derived peptide sequences of the heavy chain (HC) and light chain (LC).

From: A peptide-based anti-Adalimumab antibody assay to monitor immune response to biologics treatment in juvenile idiopathic arthritis and childhood chronic non-infectious uveitis

Peptide sequence overview

Abbreviation

Sequence

HC1

21SCAASGFTFDDYAMHVVRQAA40

HC2

50AITVNSGHIDYADSVEGRFTI70

HC3

95YCAKVSYLSTASSLDYVGQG114

HC3.1

81LQMNSLRAEDTAVYYCAKVSYLSTASSL108

HC3.2

85SLRAEDTAVYYCAKVS100

HC3.3

81LQMNSLRAEDTAVYY95

LC1

21ITCRASQGIRNYLAVYQQKP40

LC2

41AlGKAPKLLIYAASTLQSGVPS61

LC3

81EDVATYYCQRYNRAPYTFGQ100

  1. CDR regions assigned according to Kabat rules are highlighted in bold.
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