Table 3 Pearson’s χ2 and Spearman’s correlation tests between disease activity (reported as JADAS-10 and JIA inactive disease) and anti-Adalimumab peptide antibodies with two-tailed p-values.

From: A peptide-based anti-Adalimumab antibody assay to monitor immune response to biologics treatment in juvenile idiopathic arthritis and childhood chronic non-infectious uveitis

Pearson’s χ2 and Spearman’s correlation tests

 

Development group

Evaluation group

HC2

HC3

LC3

HC3

LC3

JADAS-10

0.630

0.570

0.570

0.420

0.460

Inactive, joint and eye disease, on drug

 − 0.388

 − 0.523

 − 0.523

 − 0.420

 − 0.460

p-value

0.006

0.02

0.02

0.01

0.05

0.004

0.004

0.01

0.005

  1. A significant and positive correlation was observed with peptides HC2, HC3, and LC3 in the development group and peptides HC3 and LC3 in the evaluation group.
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