Table 1 Factors and limits in the experimental design.
Operation boundary | Formulation variable | Manipulated process variable | ||
---|---|---|---|---|
Mass fraction of cellulose material (%) | Liquid to solid ratio (g/g) | Impeller speed (s−1) | Granulator scale (L) | |
Upper limit | 100 | 1.8 | 1200 | 2 |
Lower limit | 0 | 0.025 | 350 | 1 |
Type | Continuous | Continuous | Continuous | Discrete |