Table 1 The demographic data of the patients who underwent frozen autograft reconstruction on the appendicular skeleton in the three age groups.
Generation | Children (≤ 14 years old) | AYAs (15 to 39 years old) | Older adults (≥ 40 years old) | P-value |
|---|---|---|---|---|
Cases (n) | 27 | 37 | 16 | – |
Median age (years old) (range) | 11 (6–14) | 23 (15–39) | 59 (41–76) | < 0.01 |
Sex (Male: Female) | 15:12 | 20:17 | 10:6 | 0.92 |
Median follow-up periods (mos.) (range) | 87 (3–237) | 89 (5–229) | 86 (26–163) | 0.98 |
Stage (AJCC8th) (n) (%) | IIA 2 (7%) IIB 18 (67%) III 2 (7%) IVB 5 (19%) | IIA 12 (32%) IIB 14 (38%) III 2 (5%) IVA 2 (5%) IVB 7 (19%) | IIA 6 (38%) IIB 8 (50%) III 1 (6%) IVB 1 (6%) | 0.08 |
Tumor location (n) (%) | Upper extremities 2 (7%) Lower extremities 25 (93%) | Upper extremities 5 (14%) Lower extremities 32 (86%) | Upper extremities 4 (25%) Lower extremities 12 (75%) | 0.30 |
Histological types (n) (%) | Osteosarcoma 25 (93%) Ewing sarcoma 2 (7%) | Osteosarcoma 29 (78%) Ewing sarcoma 3 (8%) UPS 3 (8%) Chondrosarcoma 1 (3%) Malignant hemangiopericytoma 1 (3%) | Osteosarcoma 8 (50%) Chondrosarcoma 4 (25%) Fibrosarcoma 2 (13%) Adamantinoma 1 (6%) Malignant PMT 1 (6%) | < 0.01 |
Freezing procedures (n) (%) | Free freezing 11 (41%) Pedicle freezing 16 (59%) | Free freezing 21 (57%) Pedicle freezing 16 (43%) | Free freezing 5 (31%) Pedicle freezing 11 (69%) | 0.21 |
Reconstruction methods (n) (%) | ||||
Intercalary | 16 (59%) | 11 (30%) | 7 (44%) | 0.16 |
Osteoarticular | 5 (19%) | 10 (27%) | 2 (13%) | |
Composite | 6 (22%) | 16 (43%) | 7 (44%) | |
