Figure 6
From: LOXL2 attenuates osteoarthritis through inactivating Integrin/FAK signaling
LOXL2 restored IL-1β-mediated Collagen II degradation through Integrin/FAK pathway. (A) Flow chart of the isolation of TMJ chondrocytes and schematic diagram of agent-treated chondrocytes. (B) Western blot analysis and (C) quantitative results of LOXL2, Collagen II, Integrin β1, p-FAK and FAK expression in chondrocytes from samples treated as indicated. (D) RT-qPCR analysis of LOXL2, Collagen II, Integrin β1 and FAK expression in chondrocytes from samples treated as indicated. Error bars represent S.D. *P < 0.05, **P < 0.01.
