Table 2 Genotype frequencies of CTLA4 +49A>G (rs231775) and TGF-β1 −800G>A (rs1800468) polymorphisms in renal transplant patients receiving cyclosporine A (CsA) or tacrolimus (TAC) every 12 or 24 h.
Genotype | Patients receiving CsA (12 h) | Patients receiving TAC (12 h) | Patients receiving TAC (24 h) | P | |||
|---|---|---|---|---|---|---|---|
Observed values n (%) | Expected values % | Observed values n (%) | Expected values % | Observed values n (%) | Expected values % | ||
+49A>G CTLA4 | |||||||
AA | 59 (32.2) | 32.49 | 18 (34) | 34.81 | 48 (30.8) | 31.36 | |
AG | 90 (49.2) | 49.02 | 26 (49.1) | 48.38 | 78 (50) | 49.28 | 0.426 |
GG | 34 (18.6) | 18.49 | 9 (17) | 16.81 | 30 (19.2) | 19.36 | |
Total | 183 (100) | 100 | 53 (100) | 100 | 156 (100) | 100 | |
−800G>A TGF-β1 | |||||||
GG | 166 (90.7) | 90.25 | 45 (84.9) | 84.64 | 138 (88.5) | 88.36 | |
GA | 15 (8.2) | 9.5 | 8 (15.1) | 14.72 | 18 (11.5) | 11.28 | 0.388 |
AA | 2 (1.1) | 0.25 | 0 (0) | 0.64 | 0 (0) | 0.36 | |
Total | 183 (100) | 100 | 53 (100) | 100 | 156 (100) | 100 | |
