Figure 3
From: First identification of ITM2B interactome in the human retina
(a) Volcano plot with − log10 p-value vs. log2 FC (mouse anti-ITM2B/unspecific antibody). Each point represents an identified protein. Proteins with significantly different abundances (in red 0.01 < p-value < 0.05, in green p-value < 0.01) are above the horizontal red line. On the right side are the proteins enriched with the mouse anti-ITM2B antibody with a FC > 2 while on the left side are the proteins enriched with the unspecific antibody with FC > 2. (b) Co-immunoprecipitation of APP and APLP2 from the human retina. The IP for negative controls (NC) was performed using Dynabeads and mouse IgG (isotypic control). Raw data of Western blots are presented in Supplementary Fig. S9.
