Table 3 Bayesian TMRCA estimates for 229E, HKU1, NL63 and OC43a.

From: A comparative recombination analysis of human coronaviruses and implications for the SARS-CoV-2 pandemic

 

TMRCA (A.D)

Lower 95% HPD

Upper 95% HPD

Nucleotide Subst Model

Clock model

Demographic model

229Ea

1989

1988

1990

SYM + I + G

Strict

Constant

HKU1a

1951

1842

1998

GTR + G + I

UCLN

Bayesian Skyline

NL63b

1964

1945

1978

HKY + I

UCLN

Bayesian Skyline

OC43a

1970

1960

1978

GTR + I

UCLN

Bayesian Skyline

  1. aRecombinant genomes removed.
  2. bNon-recombinant region 13093-20198.
  3. UCLN, uncorrelated lognormal; TMRCA, time to most recent common ancestor.