Figure 6 | Scientific Reports

Figure 6

From: Development of multiplex digital PCR assays for the detection of PIK3CA mutations in the plasma of metastatic breast cancer patients

Figure 6

PIK3CA mutations detection in the plasma of 213 HR + /HER2− metastatic breast cancer patients. (a) Numbers of positive cases per mutation for the nine PIK3CA mutations found with the PIK3CA assays among the 213 HR + /HER2− metastatic breast cancer patients tested. (b) Relative frequencies of the nine PIK3CA mutations identified. (c) Distributions of the mutations in copies/ml of plasma and in MAF (%) (mutations with more than five instances are presented as box plots whereas mutations with less than five instances are presented as points, with median lines for more than two instances).

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