Figure 3
From: A virus-free cellular model recapitulates several features of severe COVID-19
Impairment of several key pathways in ACE2 overexpressing cell lines. GSEA identified several gene sets downregulated in ACE2 overexpressing cell lines. Gene sets could be grouped in pathways/networks related to senescence/chromosome maintenance (a–d), antibody production (e,f), DNA repair/viral transcription (g–i), protein folding/platelet homeostasis (j), histone modifications (k).
