Figure 4

Top pathways of differentially expressed genes (FDR < 0.05). Pathways [Z-score > 0.05, − log (p value) > 1.3] in orange predicted to be activated and pathways in blue predicted to be inhibited. The more intensity of the colours, the higher absolute z-score. The proportion of genes within the pathways that were differentially expressed are indicated by the orange line as ratios. The height of each bar refers to the − log (p-value).