Table 2 The list of the genes that significantly (z-score > 3) affected at the challenged group.

Symbol	Function of gene^a	LFC^b	FDR^c	Type(s)	HGNC^d
AGT	Angiotensinogen	14.366	0.0009	Growth factor	183
CAMK2A	Calcium/calmodulin dependent protein kinase II alpha	10.169	0.0008	Kinase	815
CAMKV	CaM kinase like vesicle associated	10.958	0.0101	Kinase	79,012
ELOVL2	ELOVL fatty acid elongase 2	10.402	0.0019	Enzyme	54,898
GABRA3	Gamma-aminobutyric acid type A receptor subunit alpha3	10.432	0.0006	Ion channel	2556
GFAP	Glial fibrillary acidic protein	12.885	0.0004	Other	2670
GPM6A	Glycoprotein M6A	12.11	0.0020	Ion channel	2823
IRX1	Iroquois homeobox 1	10.723	0.0026	Transcription regulator	79,192
MMD2	Monocyte to macrophage differentiation associated 2	11.067	0.0016	Kinase	221,938
PACSIN1	Protein kinase C and casein kinase substrate in neurons 1	10.774	0.0009	Kinase	29,993
PADI3	Peptidyl arginine deiminase 3	10.267	0.0005	Enzyme	51,702
PLP1	Proteolipid protein 1	13.157	0.0003	Other	5354
SLC15A2	Solute carrier family 15 member 2	10.478	0.0022	Transporter	6565
SLC1A3	Solute carrier family 1 member 3	13.277	0.0011	Transporter	6507
SLC6A11	Solute carrier family 6 member 11	11.937	0.0014	Transporter	6538
TTLL2	Tubulin tyrosine ligase like 2	10.69	0.0016	Other	83,887

^aIPA software was used to obtain gene’s function from the transcript identifier.
^bLFC, Log twofold change.
^cFDR, false discovery rate.
^dHGNC, Human Gene Nomenclature Committee.

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