Table 5 The multinomial logistic regression analysis to investigate the association between the expression of PD-L1 and EGFR mutations.

From: PD-L1 expression as a predictor of postoperative recurrence and the association between the PD-L1 expression and EGFR mutations in NSCLC

EGFR mutation

PD-L1 expression

1–49% versus < 1%

≥ 50% versus < 1%

Unadjusted OR

(95% CI), P

Adjusted ORa

(95% CI), P

Unadjusted OR

(95% CI), P

Adjusted ORa

(95% CI), P

Wild-type

Reference

Reference

Reference

Reference

Ex21

0.61

(0.30–1.22), 0.16

0.87

(0.41–1.85), 0.72

0.04

(0.01–0.31), < 0.001

0.10

(0.01–0.87), 0.03

Ex19

0.39

(0.17–0.88), 0.02

0.54

(0.23–1.30), 0.17

0.09

(0.02–0.46), < 0.001

0.23

(0.04–1.22), 0.08

Minor mutationb

0.83

(0.29–2.36), 0.72

1.05

(0.35–3.22), 0.93

0.25

(0.04–1.30), 0.09

0.38

(0.06–2.50), 0.31

  1. PD-L1 programmed death-ligand 1, EGFR epidermal growth factor receptor gene, OR odds ratio, CI confidence interval, Ex21 exon 21 L858R mutation, Ex19 exon19 deletion mutation.
  2. aAdjusted by age, sex, smoking status, pathological stage and histological type.
  3. bDefined as all mutations except Ex21 and Ex19.
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