Table 1 Clinical characteristics according to positive or negative cTnI.
Negative cTnI (N = 30,713) | Positive cTnI (N = 6093) | p-value | |
---|---|---|---|
Age (years) | 59 (48–70) | 67 (56–76) | < 0.001 |
Age ≥ 65 years | 11,862 (38.6) | 3457 (56.7) | < 0.001 |
Male sex | 16,726 (54.5) | 3656 (60.0) | < 0.001 |
Diabetes | 3487 (11.4) | 1222 (20.1) | < 0.001 |
Hypertension | 8632 (28.1) | 2661 (43.7) | < 0.001 |
Chronic kidney disease | 1216 (4.0) | 641 (10.5) | < 0.001 |
Smoking | 2194 (7.1) | 778 (12.8) | < 0.001 |
History of stroke | 1081 (3.5) | 392 (6.4) | < 0.001 |
History of coronary artery disease | 624 (2.0) | 305 (5.0) | < 0.001 |
History of myocardial infarction | 130 (0.4) | 122 (2.0) | < 0.001 |
Respiratory disease | 2168 (7.1) | 517 (8.5) | 0.001 |
Hepatic disease | 1386 (4.5) | 382 (6.3) | < 0.001 |
Cancer | 7711 (25.1) | 1545 (25.4) | 0.47 |
Endotracheal intubation | 418 (1.4) | 515 (8.5) | < 0.001 |
Use of vasopressors | 1223 (4.0) | 1105 (18.1) | < 0.001 |
Symptom< 0.001 | |||
Chest pain | 4871 (15.9) | 1288 (21.1) | |
Dyspnea | 4589 (14.9) | 1505 (24.7) | |
Dysuria or urologic symptom | 99 (0.3) | 26 (0.4) | |
Febrile symptom | 1711 (5.6) | 446 (7.3) | |
General weakness | 481 (1.6) | 129 (2.1) | |
Gastrointestinal symptom | 3846 (12.5) | 437 (7.2) | |
Miscellaneous | 120 (0.4) | 1 (0.0) | |
Neurologic symptom | 2072 (6.7) | 532 (8.7) | |
Non-cardiac chest pain | 303 (1.0) | 30 (0.5) | |
Not classified | 8450 (27.5) | 1313 (21.5) | |
Syncope or palpitation | 3673 (12.0) | 346 (5.7) | |
Trauma | 498 (1.6) | 40 (0.7) | |
Systolic blood pressure (mmHg) | 131 (114–149) | 127 (106–148) | < 0.001 |
Diastolic blood pressure (mmHg) | 80 (70–90) | 76 (65–88) | < 0.001 |
Heart rate (/min) | 84 (72–99) | 91 (76–111) | < 0.001 |
Mean arterial pressure ≤ 70 mmHg | 1811 (6.0) | 758 (12.6) | < 0.001 |
Heart rate > 100/min | 7463 (24.6) | 2283 (38.0) | < 0.001 |
White blood cell (× 103/mm3) | 7.6 (5.9–10.1) | 9.0 (6.7–12.7) | < 0.001 |
Hemoglobin (g/dL) | 13.2 (11.6–14.6) | 12.4 (10.6–14.1) | < 0.001 |
Platelet (× 103/mm3) | 213 (168–260) | 196 (145–250) | < 0.001 |
Creatinine (mg/dL) | 0.80 (0.65–0.99) | 1.02 (0.78–1.59) | < 0.001 |
c-reactive protein (mg/dL) | 0.22 (0.05–2.02) | 1.24 (0.18–7.42) | < 0.001 |
Frequency of cTnI test within 24 h | 1 (1–1) | 1 (1–2) | < 0.001 |