Table 3 Effect of trichlormethiazide on health-related quality of life.
Variables | Trichlormethiazide− | Trichlormethiazide+ | P value |
---|---|---|---|
KDQOL | |||
Symptoms/problems | 79.4 ± 16.6 | 86.4 ± 10.3 | 0.11 |
Effects of kidney disease | 83.1 ± 15.9 | 95.0 ± 5.6 | 0.02 |
Burden of kidney disease | 60.6 ± 21.1 | 67.5 ± 23.5 | 0.28 |
Work status | 95.0 ± 15.8 | 95.0 ± 15.8 | 1 |
Cognitive function | 89.3 ± 13.0 | 86.7 ± 25.3 | 0.61 |
Quality of social interaction | 85.3 ± 19.6 | 84.0 ± 25.0 | 0.78 |
Sleep | 57.8 ± 22.1 | 70.0 ± 16.5 | 0.07 |
Social support | 88.3 ± 27.3 | 84.2 ± 12.7 | 0.64 |
Overall health rating | 62.0 ± 18.7 | 67.0 ± 18.9 | 0.27 |
KDCS | 79.9 ± 12.1 | 83.6 ± 10.7 | 0.19 |
SF-36 | |||
Physical functioning | 87.5 ± 19.0 | 90.5 ± 8.6 | 0.43 |
Physical role functioning | 83.8 ± 18.2 | 92.5 ± 11.7 | 0.21 |
Body pain | 67.9 ± 24.7 | 69.6 ± 27.9 | 0.87 |
General health | 48.2 ± 16.4 | 55.6 ± 16.4 | 0.2 |
Vitality | 63.1 ± 12.3 | 70.0 ± 15.3 | 0.13 |
Social functioning | 86.3 ± 17.1 | 95.0 ± 8.7 | 0.02 |
Emotional role functioning | 84.2 ± 16.4 | 95.8 ± 9.0 | 0.02 |
Mental health | 75.5 ± 18.6 | 82.5 ± 14.4 | 0.23 |
PCS | 44.2 ± 11.3 | 44.7 ± 8.4 | 0.88 |
MCS | 49.3 ± 6.5 | 51.7 ± 8.7 | 0.28 |
RCS | 51.9 ± 9.9 | 57.3 ± 5.8 | 0.04 |