Table 1 The list of differently expressed synaptosomal proteins between CSIS versus Control and CSIS + Tian versus CSIS. CSIS-chronic social isolation, Tian-tianeptine.

From: Tianeptine modulates synaptic vesicle dynamics and favors synaptic mitochondria processes in socially isolated rats

Protein name

UniProtKB accession no

Gene

Ratio

Ratio

CSIS versus Control

CSIS + Tian versus CSIS

Inositol-1-monophosphatase

F1M978

Impa1

3.86

1.35

Phosphoglycerate mutase 1

P25113

Pgam1

3.77

2.14

RAB33B, member RAS oncogene family

F1LW77

Rab33b

2.54

1.76

Vesicle-associated membrane protein 2

Q19LA7

N/A

2.34

1.85

Ras-related protein Rab-2A

F1LP82

Rab2a

2.23

1.96

Glutamate dehydrogenase 1, mitochondrial

P10860

Glud1

2.07

1.32

Uncharacterized protein

A0A0G2K099

N/A

2.00

1.34

Pyruvate dehydrogenase E1 component subunit beta

A0A0G2KAM3

Pdhb

1.93

1.50

Ras-related protein Rab-3A

P63012

Rab3a

1.89

1.41

Pyruvate dehydrogenase E1 component subunit alpha

D4A5G8

Pdha1l1

1.60

1.45

Heat shock protein 86

Q6B437

N/A

5.21

0.72

Glucose-6-phosphate isomerase

Q6P6V0

Gpi

4.90

0.66

Clathrin coat assembly protein AP180

F1LRK0

Snap91

4.22

0.39

ATPase H + -transporting V1 subunit A

A0A1W2Q6N0

Atp6v1a

4.00

0.65

Endophilin-A1

O35179

Sh3gl2

3.99

0.60

Dynamin-1

P21575

Dnm1

3.89

0.63

AP-2 complex subunit alpha

A0A0G2K943

Ap2a2

3.63

0.50

Fructose-bisphosphate aldolase

A0A0G2K3Q6

Aldoc

3.52

0.68

Beta-enolase

P15429

Eno3

3.51

0.71

Phosphoglycerate kinase

M0R6Y8

RGD1560402

3.46

0.71

Alpha-1,4 glucan phosphorylase

G3V6Y6

Pygb

3.43

0.76

Pyruvate kinase

A0A0G2JVG3

Pkm

3.30

0.75

Aspartate aminotransferase, cytoplasmic

P13221

Got1

3.29

0.78

Protein kinase C and casein kinase substrate in neurons protein 1

A0A0G2JWR2

Pacsin1

3.23

0.74

Aminopeptidase

F1M9V7

Npepps

3.20

0.67

Guanine deaminase

Q9JKB7

Gda

3.19

0.75

cAMP-dependent protein kinase type II-beta regulatory subunit

A0A0G2K5G0

Prkar2b

3.12

0.64

Tubulin alpha chain

A0A0H2UHM7

LOC100909441

3.07

0.59

Tubulin beta-2A chain

P85108

Tubb2a

3.06

0.62

Tubulin beta-5 chain

P69897

Tubb5

3.00

0.63

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

P63329

Ppp3ca

2.83

0.69

Septin 7

D4A0F5

Sept7

2.83

0.75

Tubulin beta chain

G3V7C6

Tubb4b

2.74

0.71

Septin 5

D3ZT07

Sep5

2.61

0.79

Mitogen-activated protein kinase 1

P63086

Mapk1

2.53

0.74

Spectrin alpha chain, non-erythrocytic 1

A0A0G2K1Y8

Sptan1

2.44

0.73

ATPase, H + transporting, V1 subunit E isoform 1, isoform CRA_a

G3V7L8

Atp6v1e1

2.39

0.66

Vesicle-fusing ATPase

A0A0G2K6U1

Nsf

2.32

0.64

Contactin-1

Q63198

Cntn1

2.11

0.75

Syntaxin-binding protein 1

P61765

Stxbp1

1.99

0.77

Spectrin beta chain

G3V6S0

Sptbn1

1.96

0.75

Tenascin-R

F1LQ63

Tnr

1.84

0.58

Neurofascin

D3ZW56

Nfasc

1.59

0.71

  1. Proteins were identified according to MS/MS spectra search against the Uniprot/Swissprot database using the Proteome Discoverer (version 1.3) search engine (Thermo Fisher Scientific).
Back to article page