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Figure 1

From: Targeting of Uropathogenic Escherichia coli papG gene using CRISPR-dot nanocomplex reduced virulence of UPEC

Figure 1

CQDs display no cytotoxicity to both bacterial and human cells. Effect of carbon quantum dots (CQDs) on the viability of (a) Hela cells, (b) THP-1 cells (c) UPEC strain, CFT073 and (d) commensal strain K12. Cells were incubated with CQDs at different doses (i.e. 0, 12.5, 25, 50, 100 and 200 ug/ml) and proliferation was observed after 24 h and 48 h using MTT assay. The data represents an average of triplicate experiments as mean ± SEM. (e) CQD does not induce haemolysis in RBCs. Haemolysis assay of RBCs was performed with different concentration of CQDs, using PBS as negative control ( −) and 1% triton X as positive control ( +). The data represents an average of triplicate experiments as mean ± SD (one-way ANOVA, ns-not significant, p ~ 0.36).

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