Table 3 Top five biofunctions for each cluster annotated by enrichment analysis of 68 metabolites.

Cluster 1

Components of cysteine metabolism

4.0e–10

1.8e–08

Components of arginine and proline metabolism

2.1e–08

4.9e–07

Components of nitrogen metabolism

2.9e–07

4.4e–06

Components of glutamate metabolism

2.1e–06

2.4e–05

Components of glycine, serine, and threonine metabolism

5.9e–06

5.5e–05

Cluster 2

Components of glycine, serine, and threonine metabolism

1.9e–07

4.7e–06

Essential amino acids

2.9e–06

3.5e–05

Components of aminoacyl-tRNA biosynthesis

8.9e–06

5.3e–05

Components of cysteine metabolism

6.8e–06

5.3e–05

Semi-essential amino acids

5.4e–04

2.6e–03

Cluster 3

Vitamins

1.0e–06

1.8e–05

Essential amino acids

9.1e–06

6.2e–05

Essential vitamins

1.0e–05

6.2e–05

Components of purine metabolism

7.3e–05

3.3e–04

Vitamins (Vitamin C)

6.6e–04

2.2e–03