Table 2 Results of primary and secondary models comparing BDNF concentration (square-root transformed) among study groups.

From: The contribution of platelets to peripheral BDNF elevation in children with autism spectrum disorder

 

ASD versus TYP

DD versus TYP

ASD versus DD

Model 1: no covariate

Test statistic

t(164) = 2.91, p = 0.004

t(164) = 1.73, p = 0.09

t(164) = 0.44, p = 0.66

SMD [95% CI]

0.23 [0.07, 0.38]

0.14 [− 0.02, 0.29]

0.03 [− 0.12, 0.19]

Model 2: platelet covariate

Test statistic

t(156) = 2.19, p = 0.03

t(156) = 1.25, p = 0.21

t(156) = 0.41, p = 0.68

SMD [95% CI]

0.18 [0.02, 0.33]

0.10 [− 0.06, 0.26]

0.03 [− 0.13, 0.19]

  1. SMD standardized mean difference, CI confidence interval, ASD autism spectrum disorder (n = 94), TYP typical development (n = 52), DD developmental delay (n = 21). Outcome was square-root transformed BDNF (pg/mL). SMD was calculated using estimated mean difference. Model 1 was also performed with complete cases (i.e., excluding the seven TYP participants without platelet count); effect size estimates were identical to those shown in this table (see Supplementary Materials). Full results for all models are shown in the Supplementary Materials.
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