Table 1 Baseline characteristics of the study population (N = 16).

From: An investigation into the avoidability of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome

Variable description

N = 16

Reference values

Age (years)

Mean (SD)

41.5 (13.3)

–

Gender (male)

N (%)

12 (75)

–

AST median (IQR)

U/L

50 (27, 124)

5–40

ALT (U/L)

Median (IQR)

56 (22, 160)

7–56

ALP (U/L)

Median (IQR)

115 (97, 145)

44–147

Albumin (g/L)

Median (IQR)

34 (25, 38)

35–50

Neutrophils (× 103 cells/µL)

Median (IQR)

2.5 (23.5, 67)

2–7

Eosinophils (× 103 cells/μL)

Median (IQR)

4.5 (2.4, 7.5)

0.0–0.5

EGFR*7 (mL/min/1.73 m2

Median (IQR)

60 (60, 107)

> 60

Drug latent period (days)

Median (IQR)

14 (6.4, 29.2)

–

Extent of skin rash (> 50%)

9/16

 

Internal organ involvement

Liver (%)

25

 

Kidneys (%)

37.5

 

RegiSCAR

Median (IQR)

6 (5, 6.8)

 

J-SCAR

Median (IQR)

5 (4, 5.8)

 

Proportion of EBV positivity (%)

31.2

 
  1. SD Standard deviation, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, PT prothrombin time, IQR interquartile range, EGFR estimated glomerular filtration rate.
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