Figure 5
From: Photodynamic therapy outcome modelling for patients with spinal metastases: a simulation-based study

Optimized treatment plans for wavelengths of (a) 690 nm and (b) 565 nm using a 2-source configuration (2 cylindrical diffusers with a radius of 500 \(\upmu\)m). The resulting iso-fluence contours are overlaid on the 3D model, highlighting the the minimum necrotic threshold within the metastatic region (0.4 J mm\(^{-2}\)) as per the colour map shown. The total energy at the 690 nm wavelength (\(E_{total} = 2914\) J) was distributed across the 2 light-emitting cylinders as: \(E_1=1981.8\) J and \(E_2=932.4\) J, for the left and right sources respectively. At 565 nm, the total energy was \(E_{total} = {9.3}\times 10^6\) J, distributed as: \(E_1={8.35}\times 10^6\) J and \(E_2={0.95}\times 10^6\) J.