Figure 2 | Scientific Reports

Figure 2

From: Carboplatin response in preclinical models for ovarian cancer: comparison of 2D monolayers, spheroids, ex vivo tumors and in vivo models

Figure 2

In vivo response of EOC xenografts to carboplatin treatment. (A) Timeline for weekly in vivo chemotherapy cycle in our xenograft mouse model. Carboplatin was delivered intraperitoneally (IP). (B) Volume measurements of xenograft tumors (N = 8 per condition) throughout carboplatin treatment. (C) IF quantification of Ki-67 stain (normalized to control). Sensitive cell lines are indicated in green fonts, intermediate in blue and resistant in red. Data are the mean ± SEM. ns = non-significant. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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