Figure 3 | Scientific Reports

Figure 3

From: Carboplatin response in preclinical models for ovarian cancer: comparison of 2D monolayers, spheroids, ex vivo tumors and in vivo models

Figure 3

Carboplatin response of EOC 3D spheroids. Representative pictures of EOC cell lines forming at 48 h (A) compact spheroids or (B) dense aggregates. (C) Normalized viability of spheroids after a 24-h carboplatin treatment with a 24-h recovery. (D) Dose-inhibition response curves with their corresponding IC50. Sensitive cell lines are indicated in green fonts, intermediate in blue and resistant in red. Data are the mean ± SEM of three independent experiments, two replicates per condition. Scale bar on images (A, B) = 400 µm, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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