Table 1 QT prolongs with HFD diet in control mice but not MCU KO mice.

From: The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet

 

RR

PR

QRS

QT

Control

Basal

101.3 ± 1.7

31.4 ± 0.8

12.0 ± 0.1

43.8 ± 0.6

HFD 4 wks

103.3 ± 1.0

33.1 ± 0.7

12.3 ± 0.1

55.9 ± 4.0*

MCU KO

Basal

105.1 ± 1.8

32.4 ± 0.9

11.9 ± 0.3

44.6 ± 1.5

HFD 4 wks

104.6 ± 1.3

33.6 ± 0.8

12.1 ± 0.3

44.9 ± 1.7

  1. Intervals are in milliseconds, ± SEM, n = 4 each group, *p < 0.05 compared to baseline.
Back to article page