Table 2 Effects of QTN on FCA-induced alterations in serum AST, ALT, ALP, albumin, CRP, and rheumatoid factor levels.

From: Pentahydroxy flavonoid isolated from Madhuca indica ameliorated adjuvant-induced arthritis via modulation of inflammatory pathways

Treatment

AST (U/mL)

ALT (U/mL)

Alkaline phosphatase (U/L)

Albumin (g/dl)

CRP (mg/L)

Rheumatoid factor (IU/mL)

Normal

39.95 ± 3.02

33.78 ± 1.83

69.24 ± 5.42

6.52 ± 0.38

0.99 ± 0.04

0.00 ± 0.00

AIA Control

122.90 ± 2.84#

165.80 ± 7.45#

435.00 ± 11.81#

2.00 ± 0.22#

7.65 ± 0.34#

60.25 ± 1.55#

LF (10)

59.56 ± 3.74*,$

51.11 ± 5.14*,$

136.7 ± 5.59*,$

6.25 ± 0.31*,$

2.60 ± 0.24*,$

38.58 ± 1.47*,$

QTN (5)

118.70 ± 4.26

146.60 ± 3.80

423.20 ± 6.50

2.25 ± 0.26

7.02 ± 0.18

56.96 ± 1.61

QTN (10)

88.02 ± 3.71*,$

90.45 ± 3.86*,$

276.40 ± 12.82*,$

4.05 ± 0.21*,$

4.74 ± 0.27*,$

47.86 ± 1.74*,$

QTN (20)

62.75 ± 1.42*,$

52.28 ± 3.82*,$

139.30 ± 7.38*,$

5.78 ± 0.22*,$

2.67 ± 0.13*,$

38.88 ± 0.97*,$

  1. Values in parentheses indicate a dose in mg/kg (n = 6). Data were analyzed by one-way ANOVA followed by Tukey’s multiple comparisons test. For comparison with AIA-control group: *p < 0.05, comparison with normal group: #p < 0.05 and comparison with one another: $p < 0.05. AIA adjuvant-induced arthritis, LF leflunomide, QTN 3,5,7,3′,4′-pentahydroxy flavone, AST aspartate aminotransferase, ALT alanine transaminase, CRP c-reactive protein.
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