Table 3 Effects of QTN on FCA-induced alterations in hematological parameters and ESR level.

From: Pentahydroxy flavonoid isolated from Madhuca indica ameliorated adjuvant-induced arthritis via modulation of inflammatory pathways

Treatment

RBC (X 106/µL)

WBC (X 103/µL)

Hb (g/dL)

Platelets (X 109/L)

ESR (mm)

Normal

5.55 ± 0.23

5.78 ± 0.30

15.83 ± 0.52

912.80 ± 40.47

3.64 ± 0.23

AIA Control

1.95 ± 0.17#

12.45 ± 0.41#

9.81 ± 0.55#

1658.00 ± 35.94#

14.69 ± 0.27#

LF (10)

4.91 ± 0.26*,$

6.84 ± 0.29*,$

15.41 ± 0.73*,$

1013.00 ± 37.21*,$

9.97 ± 0.44*,$

QTN (5)

2.02 ± 0.21

11.92 ± 0.25

10.10 ± 0.43

1633.00 ± 38.45

14.30 ± 0.44

QTN (10)

2.94 ± 0.24*,$

9.55 ± 0.25*,$

12.16 ± 0.60*,$

1453.00 ± 37.97*,$

12.63 ± 0.42*,$

QTN (20)

4.45 ± 0.20*,$

6.96 ± 0.28*,$

15.39 ± 0.33*,$

1048.00 ± 27.22*,$

10.19 ± 0.43*,$

  1. Values in parentheses indicate a dose in mg/kg (n = 6). Data were analyzed by one-way ANOVA followed by Tukey’s multiple comparisons test. For comparison with AIA-control group: *p < 0.05, comparison with normal group: #p < 0.05 and comparison with one another: $p < 0.05. AIA adjuvant-induced arthritis, LF leflunomide, QTN 3,5,7,3′,4′-pentahydroxy flavone, RBC red blood cells, WBC white blood cells, ESR erythrocyte sedimentation rate.
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