Table 3 Potential risk factors identified by univariate and multivariate logistic regression analysis.

From: Development and validation of a discrimination model between primary PLA2R-negative membranous nephropathy and minimal change disease confirmed by renal biopsy

Variable

Univariable

Multivariable

OR (95%CI)

P

OR (95%CI)

P

Age (years)

1.053 (1.033–1.073)

 < 0.001

1.060 (1.026–1.095)

 < 0.001

Gender, n (male, %)

0.927 (0.555–1.550)

0.773

  

SBP (mmHg)

1.016 (1.000–1.032)

0.045

  

DBP (mmHg)

0.987 (0.963–1.011)

0.288

  

RBC (1012/L)

0.385 (0.243–0.611)

 < 0.001

0.244 (0.071–0.846)

0.026

WBC (109/L)

1.062 (0.932–1.210)

0.365

  

PLT (109/L)

0.993 (0.989–0.997)

0.001

  

Eos (109/L)

0.284 (0.073–1.104)

0.223

  

Eos%

0.907 (0.824–0.999)

0.108

  

Hb (g/L)

0.978 (0.965–0.991)

0.001

  

MCH (pg)

1.036 (0.914–1.174)

0.582

  

MCHC (g/L)

1.012 (0.988–1.038)

0.329

  

TP (g/L)

1.116 (1.077–1.157)

 < 0.001

  

ALB (g/L)

1.174 (1.118–1.234)

 < 0.001

1.183 (1.037–1.349)

0.012

TCHO (mmol/L)

0.656 (0.582–0.740)

 < 0.001

  

TG (mmol/L)

1.010 (0.893–1.142)

0.876

  

LDL (mmol/L)

0.647 (0.570–0.734)

 < 0.001

  

HDL (mmol/L)

0.251 (0.142–0.445)

 < 0.001

0.188 (0.083–0.426)

 < 0.001

eGFR (ml/min/1.73m2)

1.007 (0.998–1.017)

0.122

  

Scr (μmol/L)

0.992 (0.986–0.999)

0.016

  

Urea (mmol/L)

0.851 (0.775–0.934)

0.001

0.777 (0.645–0.937)

0.008

UA (μmol/L)

0.999 (0.996–1.022)

0.501

  

CRP (mg/L)

1.012 (0.983–1.041)

0.715

  

ESR (mm/h)

0.982 (0.974–0.991)

 < 0.001

  

C3 (g/L)

0.201 (0.077–0.525)

0.001

0.088 (0.015–0.507)

0.007

C4 (g/L)

0.009 (0.001–0.140)

 < 0.001

  

24hTP (g)

0.865 (0.803–0.930)

 < 0.001

  

Urine volume (L)

1.945 (1.354–2.794)

 < 0.001

  

Thrombosis, n (%)

4.255 (0.436–41.513)

0.213

  
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