Table 2 Relationships of tumor size, T stage, lymph node metastasis, tumor differentiation, age, gender, smoking status, and alcohol use with AKR1B10 expression in laryngeal carcinoma.

From: The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma

Clinical indicators

Number

AKR1B10

P

 − 

 + 

 +  + 

 +  +  + 

Gender

Male

66

23

15

21

7

0.328

Female

21

8

2

6

5

Age (years)

 ≤ 60

50

22

10

10

8

0.062

60

37

9

7

17

4

Tumor size

 ≤ 2 cm

21

16

2

3

0

 < 0.001

 > 2 cm

62

14

15

22

11

T stage

T1–T2

63

27

19

8

9

0.632

T3–T4

24

12

4

5

3

Lymph node metastasis

Yes

39

8

8

16

7

0.01

No

22

14

2

5

1

Differentiation

High

19

10

5

3

1

0.007

Medium

59

20

10

23

6

Poor

9

1

2

1

5

Smoking

Yes

36

10

10

12

4

0.195

No

51

21

13

7

10

Alcohol use

Yes

25

2

6

8

9

 < 0.001

No

62

46

7

5

4

  1.  + , weakly positive; +  + , moderately positive; +  +  + , strongly positive.
  2. All variables were analyzed using Fisher’s exact probability test, excluding age, which was analyzed using the R × C χ2 test.
  3. AKR1B10, aldosterone reductase family 1 member B10.