Figure 1 | Scientific Reports

Figure 1

From: Probenecid inhibits SARS-CoV-2 replication in vivo and in vitro

Figure 1

Probenecid potently inhibits SARS-CoV-2 replication in (A) NHBE cells and (B) Vero E6 cells. IC50 and IC90 values were calculated in NHBE cells and Vero E6 cells after treating with different probenecid concentrations. Cellular toxicity was calculated in NHBE cells and Vero E6 cells following treatment with different concentrations of probenecid and performing a cell viability assay that measured the percent toxicity based on the conversion of a redox dye (resazurin) into a fluorescent end product (resorufin) after 72 h. Figures were prepared using GraphPad Prism, v9.2, https://www.graphpad.com/updates/.

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