Table 1 Steady state concentration and ratio to protein binding adjusted IC90 value after different probenecid doses.
From: Probenecid inhibits SARS-CoV-2 replication in vivo and in vitro
Dose (mg) | Frequency | Steady state concentration (μg/ml) | Protein binding adjusted IC90 value (μg/mL) | Ratio with IC90 |
---|---|---|---|---|
600 | BID | 30.1 | 2.08 | 14 |
900 | BID | 92.5 | 2.08 | 44 |
1800 | QD | 64.9 | 2.08 | 31 |