Table 3 Relationship between p16INK4A expression and the clinicopathological factors of patients with cervical adenocarcinoma.
Factors | Patients | p16INK4A | p value | |
|---|---|---|---|---|
n = 82 | Negative n, (%) | Positive n, (%) | ||
Age (years) | ||||
< 60 | 58 | 10 (17.2) | 48 (82.8) | 0.002 |
> 60 | 24 | 12 (50.0) | 12 (50.0) | |
FIGO stage | ||||
< IIB | 58 | 10 (17.2) | 48 (82.8) | 0.002 |
≥ IIB | 24 | 12 (50.0) | 12 (50.0) | |
Histology | ||||
Non-gastric | 69 | 11 (15.9) | 58 (84.1) | < 0.0001 |
Gastric | 13 | 11 (84.6) | 2 (15.4) | |
Histology | ||||
Non-usual | 22 | 14 (63.6) | 8 (36.4) | < 0.0001 |
Usual | 60 | 8 (13.3) | 52 (86.7) | |
Metastasis Pelvic lymph node | ||||
Negative | 65 | 14 (12.5) | 51 (78.5) | 0.034 |
Positive | 17 | 8 (47.1) | 9 (52.9) | |
Metastasis Paraaortic lymph node | ||||
Negative | 79 | 21 (26.6) | 58 (73.4) | 0.796 |
Positive | 3 | 1 (33.3) | 2 (66.7) | |
LVSI ly | ||||
No | 29 | 2 (6.9) | 27 (93.1) | 0.003 |
Yes | 39 | 15 (38.5) | 24 (61.5) | |
LVSI v | ||||
No | 31 | 2 (6.5) | 29 (93.5) | 0.001 |
Yes | 39 | 16 (41.0) | 23 (59.0) | |
Tumor size (mm) | ||||
< 40 | 50 | 10 (20.4) | 40 (79.6) | 0.081 |
≥ 40 | 32 | 12 (37.5) | 10 (62.5) | |
Recurrence | ||||
No | 60 | 12 (20.0) | 48 (80.0) | 0.021 |
Yes | 22 | 10 (45.5) | 12 (54.5) | |
Died due to the disease | ||||
No | 63 | 14 (22.2) | 49 (77.8) | 0.086 |
Yes | 19 | 8 (42.1) | 11 (57.9) | |
