Table 5 Univariate and multivariate analyses of overall survival using a Cox proportional hazards model in patients with cervical adenocarcinoma.

Factor	Patients	Univariate analysis			Multivariate analysis
Factor	n = 82	HR	95% CI	p value	HR	95% CI	p value
Age (years)
< 60	58	0.58	0.233–1.446	0.243
≥ 60	24	ref
FIGO stage
< IIB	58	0.222	0.087–0.565	0.002	0.912	0.253–3.289	0.889
≥ IIB	24	ref			ref
Histology
Non-gastric type	69	0.67	0.222–2.021	0.477
Gastric type	13	ref
Tumor size (mm)
< 40	50	0.168	0.060–0.468	0.001	0.251	0.059–1.078	0.063
≥ 40	32	ref			ref
Metastasis Pelvic Lymph node
Negative	65	0.515	0.202–1.309	0.163
Positive	17	ref
Metastasis Paraaortic Lymph node
Negative	79	0.321	0.074–1.405	0.131
Positive	3	ref
Metastasis distance
Negative	81	0.026	0.002–0.283	0.003	0.095	0.008–1.170	0.066
Positive	1	ref			ref
Metastasis LVSI
No	29	0.053	0.007–0.416	0.005	0.06	0.006–0.571	0.014
Yes	39	ref			ref
p16^INK4A expression
Negative	22	ref			ref
Positive	60	0.409	0.164–1.020	0.055	0.951	0.295–3.064	0.933

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