Table 2 Clinical and analytical factors associated with subclinical atherosclerosis in patients with HIV infection.
From: Evaluation of endothelial function and subclinical atherosclerosis in patients with HIV infection
Characteristics of patients | Intima media thickness | Coronariy calcium score | ||||
|---|---|---|---|---|---|---|
n (%) or mean ± SD | < 0,9 mm (n = 54) | ≥ 0,9 mm (n = 23) | P valuea | 0–100 UA (n = 64) | > 100 UA (n = 13) | P valuea |
Male, n (%) | 31 (57.4) | 20 (87.0) | 0.01 | 40/64 (63.0) | 11/13 (84.6)11/13) | 0.12 |
Age (years) | 47.8 ± 10.4 | 55.8 ± 9.98 | 0.02 | 48.09 ± 9.93 | 60.7 ± 9.87 | 0.01 |
BMI (Kg/m2) | 25.89 ± 3.76 | 27.37 ± 4.68 | 0.14 | 26.02 ± 3.87 | 27.85 ± 4.88 | 0.14 |
MBP (mmHg) | 101.56 ± 12.07 | 106.95 ± 13.03 | 0.09 | 103.10 ± 12.8 | 103.53 ± 11.5 | 0.91 |
HIV analytical related parameters | ||||||
CD4 (cells/μl) | 715.4 ± 389.92 | 559.3 ± 283.34 | 0.04 | 707.7 ± 377.5 | 477.23 ± 235.7 | 0.01 |
CD4% | 33.2 ± 9.47 | 26.9 ± 10.99 | 0.02 | 32.0 ± 9.5 | 28.3 ± 10.6 | 0.25 |
CD4/CD8 | 0.85 ± 0.41 | 0.74 ± 0.3 | 0.06 | 0.88 ± 0.47 | 0.79 ± 0.4 | 0.54 |
Nadir CD4 (cells/μl) | 269.5 ± 172.5 | 236.9 ± 168.2 | 0.45 | 345.4 ± 182.9 | 207.7 ± 148.1 | 0.04 |
Zenith VL (copies/ml) | 15 × 104 ± 17 × 104 | 25.9 × 104 ± 8 × 104 | 0.36 | 7 × 104 ± 5 × 104 | 23.4 × 104 ± 19 × 104 | 0.02 |
HIV clinical related parameters | ||||||
Months since diagnosis HIV | 206.04 ± 89.52 | 222.60 ± 68.64 | 0,43 | 211.20 ± 84.84 | 210.36 ± 80.88 | 0.84 |
HAART (months) | 166.78 ± 80.37 | 178.47 ± 61.80 | 0,49 | 169.53 ± 76.97 | 173.92 ± 67.84 | 0.97 |
Lipid profile | ||||||
T Col (mg/dl) | 185.69 ± 59.7 | 178.64 ± 46.1 | 0.57 | 183.11 ± 52.7 | 169.15 ± 34.87 | 0.36 |
HDLCol (mg/dl) | 55.04 ± 21.76 | 49.37 ± 16.18 | 0.21 | 51.03 ± 18.2 | 51.23 ± 18.08 | 0.90 |
LDLCol (mg/dl) | 107.68 ± 33.28 | 110.22 ± 34.5 | 0.76 | 110.92 ± 33.91 | 96.30 ± 29.14 | 0.15 |
Tryglicerides (mg/dl) | 153.51 ± 54.9 | 130.82 ± 54.9 | 0.44 | 154.18 ± 124.12 | 110.08 ± 50.73 | 0.21 |
