Table 4 Clinical and analytical factors associated with EPCs in patients with HIV infection and the relationship with subclinical atherosclerosis.

From: Evaluation of endothelial function and subclinical atherosclerosis in patients with HIV infection

  

Very Early EPCs

Early EPCs

CD34 + 309 + 133 + 

CD34 + 309 + 133-

n

cells/µl

(Mean ± SD)

P valuea

cells/µl

(Mean ± SD)

P valuea

HIV analytical related parameters

Nadir CD4 (cells/ μl)

 < 350

61

0.335 ± 0.606

 

0.144 ± 0.218

 

 ≥ 350

16

0.913 ± 2.214

0.07

0.654 ± 1.786

0.03

Zenith VL (copies/ml)

 < 200,000

42

0.554 ± 1.30

 

0.313 ± 0.963

 

 ≥ 200,000

35

0.123 ± 0.17

0.20

0.059 ± 0.076

0.31

HIV clinical related parameters

Time of infection (years)

 < 20

32

0.318 ± 0.578

 

0.156 ± 0.245

 

 ≥ 20

45

0.666 ± 0.245

0.28

0.397 ± 0.284

0.33

Time of HAART (months)

 < 200

41

0.291 ± 0.396

 

0.152 ± 0.220

 

 ≥ 200

36

0.682 ± 1.711

0.21

0.381 ± 1.281

0.34

 > 1 year from diagnosis to HAART

Yes

41

0.308 ± 0.598

 

0.373 ± 1.239

 

No

36

0.639 ± 1.583

0.254

0.153 ± 0.237

0.31

Subclinical atheroesclerosis

IMT

 < 0,9

54

0.460 ± 1.285

 

0.298 ± 1.000

 

 ≥ 0,9

23

0.445 ± 0.787

0.95

0.143 ± 1.286

0.30

CACS

 < 10 AU

56

0.388 ± 0.640

 

0.176 ± 0.241

 

 ≥ 10AU

21

0.622 ± 1.913

0.58

0.437 ± 1.540

0.44

  1. EPCs endothelial progenitor cells, VL viral load dl, HAART highly active antiretroviral therapy, SD standard deviation, IMT intima media thickness, CACs coronary artery calcium score.
  2. aTwo-tailed one-way ANOVA test.