Table 2 Linear regression for the association of cEPC counts with clinical assessments related to major depressive disorder.

From: Associations between increased circulating endothelial progenitor cell levels and anxiety/depressive severity, cognitive deficit and function disability among patients with major depressive disorder

 

Immature (CD34+KDR+CD133+)

Mature (CD34+KDR+)

Univariate

Multivariate

Univariate

Multivariate

β (95% C.I.)

p-value

β (95% C.I.)

p-value

β (95% C.I.)

p-value

β (95% C.I.)

p-value

SBP

0.35 (0.14, 0.55)

0.001

0.55 (0.24, 0.86)

0.001

0.48 (0.24, 0.72)

< 0.001

0.77 (0.37, 1.17)

< 0.001

DBP

0.40 (0.12, 0.67)

0.006

  

0.55 (0.22, 0.87)

0.001

  

HAMD

1.09 (0.25, 1.93)

0.012

  

1.30 (0.28, 2.32)

0.014

  

MADRS

0.57 (− 0.05, 1.18)

0.072

  

0.70 (− 0.05, 1.45)

0.067

  

HAMA

1.18 (0.24, 2.12)

0.015

1.35 (0.39, 2.31)

0.007

1.14 (− 0.03, 2.31)

0.057

1.35 (0.12, 2.57)

0.033

DSST

− 0.32 (− 0.53, − 0.12)

0.002

  

− 0.41 (− 0.66, − 0.15)

0.002

  

PDQ-D

0.74 (0.15, 1.32)

0.015

  

0.92 (0.22, 1.62)

0.011

  

DSSS (total)

0.27 (0.07, 0.48)

0.009

  

0.31 (0.07, 0.56)

0.012

  

DSSS-DS

0.50 (0.17, 0.84)

0.003

  

0.60 (0.20, 0.99)

0.004

  

DSSS-SS

0.44 (− 0.03, 0.90)

0.064

  

0.48 (− 0.07, 1.03)

0.089

  

DSSS-PS

0.43 (− 0.43, 1.30)

0.323

  

0.47 (− 0.57, 1.50)

0.373

  

SF12-PCS

− 0.08 (− 0.55, 0.39)

0.737

  

0.01 (− 0.55, 0.57)

0.968

  

SF12-MCS

− 0.31 (− 0.53, − 0.09)

0.006

  

− 0.37 (− 0.63, − 0.11)

0.006

  

SDS (work/school)

0.99 (− 0.03, 2.01)

0.057

  

1.00 (− 0.23, 2.22)

0.109

  

SDS (social)

1.33 (0.32, 2.35)

0.010

  

1.38 (0.16, 2.60)

0.028

  

SDS (family life)

1.04 (− 0.05, 2.12)

0.061

  

1.05 (− 0.25, 2.35)

0.113

  

SDS (total)

2.90 (0.54, 5.25)

0.016

  

3.30 (0.48, 6.11)

0.022

  

GAF

− 0.50 (− 1.13, 0.13)

0.116

  

− 0.56 (− 1.33, 0.21)

0.153

  
  1. Bold italicised values represent the p-values less than 0.05.
  2. cEPCs circulating endothelial progenitor cells, SBP systolic blood pressure, DBP diastolic blood pressure, HAMD Hamilton Depression Rating Scale, MADRS Montgomery–Åsberg Depression Rating Scale, DSST Digit Symbol Substitution Test, HAMA Hamilton Anxiety Rating Scale, PDQ-D Perceived Deficits Questionnaire-Depression, DSSS Depression and Somatic Symptom Scale, DSSS-DS DSSS-Depression Subscale, DSSS-SS DSSS-Somatic Subscale, DSSS-PS DSSS-Pain Subscale, SF12-PCS Physical Component Summary of the 12-Item Short Form Health Survey, SF12-MCS Mental Component Summary of the 12-Item Short Form Health Survey, SDS Sheehan Disability Scale, GAF Global Assessment of Functioning Scale.
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