Table 2 Parametric (Pearson’s rp) and nonparametric (Spearman’s rs) correlations analysis results. Correlation assessment performed between glutamate and GABA levels obtained in biochemical ELISA tests and MTR and CEST contribution calculated at 3.0 ppm in the cortex and hippocampus of the stressed group (*p < 0.05, **p < 0.01 and ***p < 0.001).

From: Saturation transfer MRI is sensitive to neurochemical changes in the rat brain due to chronic unpredictable mild stress

 

Glutamate level

GABA level

Pearson's rp

Pearson's rp

Spearman's rs

Hippocampus

MTR: 3.0 ppm

0.5 µT

0.73*

0.55

 

0.75 µT

− 0.14

0.72*

 

CEST contribution: 3.0 ppm

0.5 µT

0.33

0.62*

 

0.75 µT

0.40

0.76*

 

Cortex

MTR: 3.0 ppm

0.5 µT

0.83**

 

− 0.30

0.75 µT

0.92***

 

0.11

CEST contribution: 3.0 ppm

0.5 µT

0.49

 

0.60

0.75 µT

0.37

 

0.03

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