Table 1 General clinical information of participants in different groups.

From: Distinguishing feature of gut microbiota in Tibetan highland coronary artery disease patients and its link with diet

Participant characteristics

HTC (n = 8)

HTN (n = 34)

HHC (n = 14)

HHN (n = 35)

LHC (n = 14)

LHN (n = 35)

p

F/K

Age, years

57.6 ± 9.7

52.4 ± 6.5

58.4 ± 12.1

51.5 ± 7.3

54.9 ± 8.3

53.0 ± 6.8

0.053

2.251

Sex, male/%

5 / 62.5%

23 / 67.6%

10 / 62.5%

20 / 57.7%

10 / 71.4%

21 / 60.0%

0.909

1.532

BMI, Kg/m2

24.4 ± 1.9

23.7 ± 4.5

23.9 ± 1.2

23.5 ± 1.1

25.1 ± 2.1

24.0 ± 2.1

0.488

0.893

Smoking, n/%

1 / 12.5%

8 / 23.5%

8 / 57.1%

7 / 20.0%

5 / 35.7%

10 / 28.6%

0.121

8.723

SBP, mmHg

121.0 ± 12.1

119.2 ± 4.4

121.2 ± 6.3

118.0 ± 4.1

124.9 ± 14.2

120.3 ± 8.4

0.114

1.861

DBP, mmHg

75.1 ± 5.8

76.5 ± 6.3

78.6 ± 5.4

78.6 ± 3.6

75.6 ± 7.8

76.3 ± 7.5

0.367

1.093

TC, mmol/L

3.89 ± 0.88

4.23 ± 1.04

3.34 ± 0.49

4.36 ± 1.14

3.30 ± 0.89

4.13 ± 0.64

0.001

4.732

TG, mmol/L

1.92 ± 0.66

1.52 ± 0.73

1.58 ± 0.57

1.71 ± 0.97

1.54 ± 0.68

1.29 ± 0.53

0.161

1.613

LDL-c, mmol/L

2.10 ± 0.94

2.82 ± 0.94

1.97 ± 0.56

2.67 ± 0.87

1.84 ± 0.79

2.30 ± 0.80

0.001

4.658

ALT (U/I)

26.00 ± 7.80

25.79 ± 7.21

26.43 ± 7.23

28.14 ± 8.93

26.07 ± 8.77

27.06 ± 9.39

0.322

0.899

AST (U/I)

23.63 ± 5.40

24.12 ± 6.99

24.21 ± 6.70

24.11 ± 7.39

25.86 ± 9.25

24.40 ± 6.65

0.156

0.978

BUN (mmol/L)

4.35 ± 1.53

3.90 ± 0.97

4.53 ± 1.51

4.27 ± 1.12

4.28 ± 1.30

4.00 ± 1.17

0.841

0.523

Creatinine (umol/L)

68.13 ± 11.22

70.15 ± 13.34

69.29 ± 13.62

70.23 ± 10.93

70.21 ± 10.24

67.29 ± 10.66

0.318

0.901

Fasting blood glucose (mmol/L)

4.37 ± 0.62

4.41 ± 0.68

4.57 ± 0.81

4.48 ± 0.67

4.66 ± 0.51

4.62 ± 0.61

0.611

0.692

CRP (mg/L)

4.4 ± 1.4

4.6 ± 1.5

4.3 ± 1.1

4.9 ± 1.4

4.1 ± 1.1

4.9 ± 1.4

1.366

0.241

Cardiac function and geometry

LA(mm)

34.4 ± 1.4

33.7 ± 3.2

33.3 ± 3.0

33.2 ± 3.1

35.9 ± 4.1

34.1 ± 3.4

1.575

0.171

LVEDD(mm)

45.1 ± 2.8

46.1 ± 5.0

46.4 ± 5.0

45.9 ± 4.3

46.6 ± 5.3

46.7 ± 5.0

0.202

0.961

IVS (mm)

7.4 ± 1.2

7.4 ± 0.9

7.3 ± 1.0

7.5 ± 1.0

7.6 ± 1.3

7.0 ± 1.0

1.117

0.354

RA(mm)

35.0 ± 3.5

34.2 ± 3.4

33.6 ± 3.6

34.5 ± 3.9

34.1 ± 2.9

34.4 ± 2.8

0.227

0.950

RV(mm)

22.9 ± 2.2

25.4 ± 4.5

23.1 ± 2.9

24.2 ± 3.8

25.0 ± 4.2

25.9 ± 4.6

1.616

0.160

EF(%)

59.3 ± 0.7

61.4 ± 5.9

63.1 ± 9.6

60.6 ± 5.7

61.8 ± 5.9

61.1 ± 5.1

0.570

0.723

No. of stenosed vessels

Single-vessel, n / %

4 / 50.0%

6 / 42.9%

8 / 57.1%

NA

NA

NA

2.087

0.352

Double-vessel, n / %

1 / 12.5%

3 / 21.4%

4 / 28.6%

NA

NA

NA

0.769

0.681

Triple-vessel, n / %

3 / 37.5%

5 / 35.7%

2 / 14.3%

NA

NA

NA

0.488

0.893

Time since last chest pain (h)

3.6 ± 1.3

4.1 ± 1.4

4.1 ± 1.1

NA

NA

NA

0.381

0.686

  1. For normally distributed measurement data and categorical variables, values are expressed as mean ± standard deviation (SD) and number / the percentage (n / %), respectively. P and F / K values are shown in the right column of the table, and p < 0.05 was considered statistically significant.
  2. CAD coronary artery disease, QTP Qinghai-Tibet Plateau, HTC the Tibetan CAD patients residing at QTP, HTN the Tibetan healthy individuals residing at QTP, HHC the Han CAD patients residing at QTP, HHN the Han healthy individuals residing at QTP, LHC the Han CAD patients from sea level in southern China, LHN the Han healthy individuals from sea level in southern China, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglyceride, LDL-c low-density lipoprotein cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase, BUN urea nitrogen, CRP c-reactive protein, LA left atrium diameter, RA right atrium diameter, IVS interventricular septal thickness, LVEDD left ventricular end-diastolic diameter, RV right ventricle diameter, EF% ejection fraction, NA not available.
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