Figure 7
From: Vm-related extracellular potentials observed in red blood cells
(A) A schematic showing ion concentrations in proximity to the cell surface in high ionic strength (HIS) and low ionic strength (LIS) solutions. Where the surface potential of a cell is negative, it will electrostatically attract cations from solution, raising the cation concentration at the surface whilst depleting anions. Where the surface potential is positive, this situation is reversed, with the cation level in HIS solutions reaching similar values to those observed in LIS solutions. (B) A comparison of the voltage-gated cation channel behaviour reported by Kaestner et al.26, and the cation concentration at the surface relative to the bulk (green line) determined using the Poisson-Boltzmann equation, using ζ determined from Eq. (5).
